The rapidly advancing fields of proteomics and metabolomics may provide the tools necessary to develop predictive tools and tests for early and accurate screening of devastating mental illnesses such as schizophrenia and manic depression....
PLoS Med. 2006 Nov;3(11):e428.
Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis.
"....application of modern proteomics techniques, particularly mass spectrometric approaches, holds the potential to advance the understanding of the biochemical basis of psychiatric disorders and may in turn allow for the development of diagnostics and improved therapeutics."
PLoS Med. 2006 Aug;3(8):e327.
Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia.
Short-term treatment with atypical antipsychotic medication resulted in a normalization of the CSF disease signature in half the patients well before a clinical improvement would be expected. Furthermore, our results suggest that the initiation of antipsychotic treatment during a first psychotic episode may influence treatment response and/or outcome.
No biological basis for mental illness?
"There is nothing more frightful than ignorance in action" Goethe
PLoS Med. 2006 Nov;3(11):e428.
Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis.
"....application of modern proteomics techniques, particularly mass spectrometric approaches, holds the potential to advance the understanding of the biochemical basis of psychiatric disorders and may in turn allow for the development of diagnostics and improved therapeutics."
PLoS Med. 2006 Aug;3(8):e327.
Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia.
Short-term treatment with atypical antipsychotic medication resulted in a normalization of the CSF disease signature in half the patients well before a clinical improvement would be expected. Furthermore, our results suggest that the initiation of antipsychotic treatment during a first psychotic episode may influence treatment response and/or outcome.
No biological basis for mental illness?
"There is nothing more frightful than ignorance in action" Goethe
