Here a couple blogs posts worth reading this Friday…
Derek Lowe on where drugs come from:
We can now answer the question: "Where do new drugs come from?". Well, we can answer it for the period from 1998 on, at any rate. A new paper in Nature Reviews Drug Discovery takes on all 252 drugs approved by the FDA from then through 2007, and traces each of them back to their origins. What's more, each drug is evaluated by how much unmet medical need it was addressed to and how scientifically innovative it was. Clearly, there's going to be room for some argument in any study of this sort, but I'm very glad to have it, nonetheless. Credit where credit's due: who's been discovering the most drugs, and who's been discovering the best ones?
First, the raw numbers. In the 1997-2005 period, the 252 drugs break down as follows. Note that some drugs have been split up, with partial credit being assigned to more than one category. Overall, we have:
58% from pharmaceutical companies.
18% from biotech companies..
16% from universities, transferred to biotech.
8% from universities, transferred to pharma.
18% from biotech companies..
16% from universities, transferred to biotech.
8% from universities, transferred to pharma.
Read more here.
Orac on what it means to be “anti-vaccine”:
I regularly throw that word around -- and, most of the time, with good reason. Many skeptics and defenders of SBM also throw that word around, again with good reason most of the time. There really is a shocking amount of anti-vaccine sentiment out there. But what does "anti-vaccine" really mean? What is "anti-vaccine"? Who is "anti-vaccine"? Why? What makes them "anti-vaccine"?
Believe it or not, for all the vociferousness with which I routinely go after anti-vaccine loons, I'm actually a relative newcomer to the task of taking on the anti-vaccine movement. Ten years ago, I was blissfully unaware that such a movement even existed; indeed, I doubt the concept would even have entered my brain that anyone would seriously question the safety and efficacy of vaccines, which are one of the safest and most efficacious preventative medical interventions humans have ever devised, arguably having saved more lives than any other medical intervention ever conceived. Even six years ago, although I had become aware of the existence of the anti-vaccine movement by that time, when I considered anti-vaccine loons at all, I considered them a small bunch of cranks so far into the woo that they weren't really worth bothering with. Yes, I was a shruggie.
Read more here.
